Titlebook: Uncommon Diseases in the ICU; Marc Leone,Claude Martin,Jean-Louis Vincent Book 2014 Springer International Publishing Switzerland 2014 Dia

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Genetic Aspects of Uncommon Diseasesprevalence below 1/2,000. This chapter presents general data on the pathophysiology of these diseases and their diagnosis. The most frequent hereditary diseases that can be encountered in the ICU are listed with details in summary tables.

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Dengue in the Intensive Care Unit and dengue shock syndrome, which presents as fever, haemorrhaging with thrombopenia, and a state of shock due to capillary leak. There is no effective aetiological treatment for this disease. Treatment consists essentially of the management of shock and correction of haemorrhagic problems. A vaccine against dengue is currently under development.

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Scintillations

Brugada Syndromes associated with syncope or malaise. This syndrome is characterized by ECG abnormalities including various aspects of ST segment elevation. Arrhythmogenicity can be favoured by various drugs (antiarrhythmics, psychotropes), hyperthermia, alcohol, abnormal potassium and calcium serum concentrations.

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