Titlebook: Ultrastructure of Skeletal Tissues; Bone and Cartilage i E. Bonucci,P. M. Motta Book 1990 Kluwer Academic Publishers 1990 bone.cartilage.fr

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Factual

The original contributions of the scanning electron microscope to the knowledge of bone structure, for some years it appeared unable to offer much more than a mere three-dimensional visualization of structures whose morphology had already been deduced from two-dimensional studies with the light microscope (LM) and the transmission electron microscope (TEM). For this reason, the SEM was felt to b

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Ultrastructure of cartilage, characteristics of the intercellular substance, which are realized through the unique interrelationships existing between its solid and aqueous phases. The organic components important in this respect are collagen and proteoglycan molecules [1–4].

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Ultrastructural localization of calcium in normal and pathologic cartilage,tural level in normal mineralizing cartilage and in cases of cartilage pathologies. In general, calcium can be found in various forms in mineralizing tissues: ionic, covalently bound to a carrier (such as enzymes, calcium-binding proteins, glycoproteins, or glycolipids), or in a solid phase such as

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Glucocorticoid effects on the ultrastructure of epiphyseal cartilage,senchymal cells group together, change their configuration, and become centers of chondrification known as precartilage. As cells enlarge and differentiate, they secrete a matrix that is metachromatic. The matrix gradually increases in amount and separates the chondroblastic cells one from another,

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Ultrastructural aspects of osteochondrodysplasias,ed and identical syndromes were described under multiple headings, whereas dissimilar disorders were treated as one. Even the newest methods of investigation frequently fail to reveal clear-cut boundaries between some of these genetically distinct types, which now number at least 50.

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The ultrastructure of the cartilaginous tumors, are much more frequent than chondrosarcomas, which comprise about 7% of all bone tumors and 10–12.5% of malignant bone tumors [1,2], being the second most frequent malignant tumor. Most benign tumors are classified as chondromas and are subclassified, according to their location, as enchondromas (c