| 書目名稱 | Tumor Dormancy, Quiescence, and Senescence, Volume 2 | | 副標(biāo)題 | Aging, Cancer, and N | | 編輯 | M.A. Hayat | | 視頻video | http://file.papertrans.cn/931/930785/930785.mp4 | | 概述 | Role of Dormancy in various cancer types is explained.Role of Senescence in the aging process is also included.Mechanisms underlying premature cellular senescence is detailed.The discussion in chapter | | 叢書名稱 | Tumor Dormancy and Cellular Quiescence and Senescence | | 圖書封面 |  | | 描述 | In this second volume in the series exploring Tumor Dormancy, Quiescence, and Cellular Senescence, discussion is focused on the role of tumor dormancy in diseases such?as breast cancer, melanoma, prostate cancer, liver cancer and lung cancer. M. A. Hayat, the series editor, writes in the preface that little is known of factors regulating the transition of residual cancer into a dormant state or the subsequent reinitiation of growth. A majority of us, he says, have in situ tumors that may remain dormant or may progress into a lethal form of cancer; the former are prevented from recruiting their own blood supply. Section I covers Molecular Mechanisms, with chapters on the role of NAE inhibitor MLN4924; oncogene-induced senescence; the role played by mitogen-activated protein kinase in the induction of cellular senescence; mechanisms of premature cell senescence and other topics. Section II examines Tumor and Cancer, discussing defects in chromatin structure and diseases; the role of fibrosis in tumor progression and the dormant to proliferative switch; the function of ING proteins in cancer and senescence and more. The final section is devoted to Stem Cells and Cancer Stem Cells, fea | | 出版日期 | Book 2014 | | 關(guān)鍵詞 | Cancer Stem cells and dormancy; Cancer diagnosis; Senescent-derived pluripotent stem cells; Therapeutic | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-007-7726-2 | | isbn_softcover | 978-94-024-0766-2 | | isbn_ebook | 978-94-007-7726-2 | | copyright | Springer Science+Business Media Dordrecht 2014 |
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