Titlebook: Topics in Nucleic Acid Structure; Stephen Neidle Book 1981 The Contributors 1981 acid.nucleic acid.structure

頌揚(yáng)本人

NMR studies of oligonucleotides in solution, in aqueous solution as determined by NMR spectroscopy. Early NMR work on oligonucleotide conformations in solution was limited to investigations of base stacking and sugar ring pucker from base proton chemical shifts and anomeric proton spin coupling constants (Bangerter and Chan, 1969; Chan and Ne

Breach

The secondary structures of polynucleotide chains as revealed by x-ray diffraction analysis of fibers, analyses of fibrous specimens. The diffraction from oriented (and sometimes polycrystalline) fibres of the polynucleotides is insufficient by itself to define conformations very accurately since diffraction signals corresponding to spacings less than 3 ? are scarce. However, it is possible to suppl

蚊帳

The solution structure of transfer RNA studied by proton NMR,quence of the first tRNA molecule was determined by Holley and coworkers (Holley .., 1965). The primary sequence led to the prediction of the well-known cloverleaf secondary structure which has been amply corroborated by the determination of over 80 tRNA sequences in the last ten years (Sprinzl ..,

環(huán)形

gerontocracy

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