| 書目名稱 | The Sticky Synapse | | 副標(biāo)題 | Cell Adhesion Molecu | | 編輯 | Hisashi Umemori,Michael Hortsch | | 視頻video | http://file.papertrans.cn/921/920560/920560.mp4 | | 概述 | Includes supplementary material: | | 圖書封面 |  | | 描述 | The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, | | 出版日期 | Book 2009 | | 關(guān)鍵詞 | evolution; molecular mechanisms; neurobiology; neurons; proteins | | 版次 | 1 | | doi | https://doi.org/10.1007/978-0-387-92708-4 | | isbn_softcover | 978-1-4899-8289-6 | | isbn_ebook | 978-0-387-92708-4 | | copyright | Springer-Verlag New York 2009 |
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