| 書(shū)目名稱 | Techniques in Prion Research | | 編輯 | Sylvain Lehmann,Jacques Grassi | | 視頻video | http://file.papertrans.cn/902/901593/901593.mp4 | | 概述 | Topical methodology volume.Detailed description of techniques currently used for the study of prion diseases.Written by experienced scientists involved in prion research since many years | | 叢書(shū)名稱 | Methods and Tools in Biosciences and Medicine | | 圖書(shū)封面 |  | | 描述 | .Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin...Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs...This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical do | | 出版日期 | Book 2004 | | 關(guān)鍵詞 | Animal Models; Antibody Production; BSE; CJD; Cell Culture Models; Cytotoxicity; Decontamination; PrP; Purif | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-0348-7949-1 | | isbn_softcover | 978-3-7643-2224-3 | | isbn_ebook | 978-3-0348-7949-1 | | copyright | Springer Basel AG 2004 |
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