Titlebook: Systems Pharmacology and Pharmacodynamics; Donald E. Mager,Holly H.C. Kimko Book 2016 American Association of Pharmaceutical Scientists 20

Modicum

Systems Pharmacology: An Overview modules regulating the cellular state. Dynamic modeling and sensitivity analysis allow the identification of robust and fragile nodes within these modules to identify putative drug targets for single or combinatorial drug treatment. Traditional pharmacokinetic and pharmacodynamic modeling complemen