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Titlebook: Structure and Dynamics of RNA; P. H. Knippenberg,C. W. Hilbers Book 1986 Springer Science+Business Media New York 1986 DNA.X-ray.acid.deve

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發(fā)表于 2025-3-21 18:52:21 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Structure and Dynamics of RNA
編輯P. H. Knippenberg,C. W. Hilbers
視頻videohttp://file.papertrans.cn/881/880182/880182.mp4
叢書名稱NATO Science Series A:
圖書封面Titlebook: Structure and Dynamics of RNA;  P. H. Knippenberg,C. W. Hilbers Book 1986 Springer Science+Business Media New York 1986 DNA.X-ray.acid.deve
描述This volume contains contributions from the speakers at the NATO Advanced Research Workshop on "3D 5tructure and Dynamics of RNA", which was held in Renesse, The Netherlands, 21 - 24 August, 1985. Two major developments have determined the progress of nucleic acid research during the last decade. First, manipulation of genetic material by recombinant DNA methodology has enabled detailed studies of the function of nucleic acids in vivo. 5econd, the use of powerful physical methods, such as X-ray diffraction and nuclear magnetic resonance spectroscopy, in the study of biomacromolecules has provided information regarding the structure and the dynamics of nucleic acids. Both developments were enabled by the advance of synthetic methods that allow preparation of nucleic acid molecules of required sequence and length. The basic understanding of nucleic acid function will ultimately depend on a close collaboration between molecular biologists and biophy- sicists. In the case of RNA, the ground rules for the formation of secondary structure have been derived from physical studies of oligoribonucleotides. Powerfull spectroscopic techniques have revealed more details of ~~A structure includi
出版日期Book 1986
關(guān)鍵詞DNA; X-ray; acid; development; diffraction; dynamics; information; kinetics; magnetic resonance; magnetic res
版次1
doihttps://doi.org/10.1007/978-1-4684-5173-3
isbn_softcover978-1-4684-5175-7
isbn_ebook978-1-4684-5173-3
copyrightSpringer Science+Business Media New York 1986
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發(fā)表于 2025-3-21 20:56:28 | 只看該作者
A Better Way to Make RNA for Physical Studies, this laboratory to synthesize RNA by joining shorter fragments with T4 RNA ligase have also succeeded in preparing fragments up to 20 nucleotides long, but yield only very small amounts of material (2).
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Improved Parameters for Prediction of RNA Secondary Structure and Insights into why RNA forms Doubltant determinants of RNA stability, but that hydrophobic bonding is not. The improved thermodynamic parameters are applied to predict secondary structures for the self splicing intervening sequence from the ribosomal RNA precursor of ..
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Picosecond Time Domain Spectroscopy of Structure and Dynamics in Nucleic Acids,ve excitation of purines and pyrimidines is available and information on the distribution and dynamics of conformational states as well as on internal motions of nucleic acid chains and individual nucleotides can be obtained.
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Improved Parameters for Prediction of RNA Secondary Structure and Insights into why RNA forms Doublovide free energy changes associated with base pairs, dangling ends, and base mismatches. The results suggest base stacking and base pairing are important determinants of RNA stability, but that hydrophobic bonding is not. The improved thermodynamic parameters are applied to predict secondary struct
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Picosecond Time Domain Spectroscopy of Structure and Dynamics in Nucleic Acids, vibrational and rotational modes as well as of short lived excited states in nucleotides and nucleic acids. With the tunability of dye lasers selective excitation of purines and pyrimidines is available and information on the distribution and dynamics of conformational states as well as on internal
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發(fā)表于 2025-3-23 08:43:54 | 只看該作者
Z-RNA: A Left-Handed Double Helix, This is the first major conformational change found in double-stranded RNA.. Therefore it is important to corroborate this observation, to characterize the conditions that produce Z-RNA, and to determine some of the properties of this novel left-handed structure. This article is a summary of our re
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