Titlebook: Structural and Functional Aspects of Enzyme Catalysis; 32. Colloquium, 23. Hermann Eggerer,Robert Huber Conference proceedings 1981 Spring

平常

Human Latent PMN Leukocyte Collagenase and Regulation of Activity via Disulfide-Thiol Interchange as molecular weight of 10,000–20,000. In previous years various proteolytic enzymes have been used by many groups to activate latent collagenases obtained from a variety of other tissues and a multistep scheme has been proposed for collagenase activation by limited proteolysis [6–9].

包裹

The Neural and Hormonal Control of Glycogen Metabolism in Mammalian Skeletal Musclerable molecular detail and it continues to act as the model to which all others are compared. This paper will summarize the major advances that have taken place over the past three years. Work up to July 1976 [5] and March 1978 [6] has been reviewed previously.

overrule

徹底明白

How Do Enzymes Work?e of the rate enhancement factors of 10. to 10. sometimes observed. However, these studies have shown that enzymes have a surprisingly reproducible structure over the many unit cells of a crystal, although the intrinsic disorder of some side chains and polypeptide backbone leave clear indications of

啞劇

Design of Synthetic Molecular Receptors and Catalystsstructure, they fold up into a tertiary structure, maintained mainly by noncovalent interactions, which delineates three-dimensional crevices and cavities, whose size, shape, and binding sites are complementary to those of the substrate.

jealousy

ARCHE

Dynamics of Molecular Recognition in Enzyme-Catalyzed Reactionsto a specific macromolecular binding site. Among the examples for this observation we find substrate enzyme and hormone receptor reactions as well as metal ion activation of proteins and other functionally important biomacromolecular processes. Frequently, the ligand-binding phase is described in an

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搬運(yùn)工

Optimum

Active Site Metals as Probes of Local Conformation and Function of Enzymesolecules, muscle contraction, nerve conduction, and transport. Cobalt, copper, iron, magnesium, manganese, molybdenum, nickel, zinc, and yet others are known to be essential, many of them in the mechanism of action of particular enzymes.