Titlebook: Statistical Methods for Quality of Life Studies; Design, Measurements Mounir Mesbah,Bernard F. Cole,Mei-Ling Ting Lee Book 2002 Springer-Ve

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Regulatory Aspects of Quality of Lifealready licensed product. Studies of this sort should be double blinded, randomized and use validated questionnaires. The duration of the study should be appropriate for the indication. Missing values can be a serious problem and plans for handling them should be included. Sensitivity analyses are i

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Application of the Multiattribute Utility Theory to the Development of a Preference-Based Health-Relomic evaluations in North America and in international multicentre studies. As the HUI3 consists of 8 attributes deliberately selected to be structurally independent and specifies 5 or 6 levels by attribute, the explicit approach of the multiattribute utility theory (MAUT) provides an efficient fram

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Strategy and Methodology for Choice of Items in Psychometric Measurement: Designing a Quality of Lifgful content. Standard scale construction has three stages: a qualitative stage, designed to achieve coverage of all potentially affected areas, a quantitative stage designed to test instrument scaling properties, and a stage of item selection to address feasibility and acceptability of the scale. T

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Analyzing Longitudinal Health-Related Quality of Life Data: Missing Data and Imputation Methodsssing data, multiplicity of outcomes, and longitudinal data structure complicate the statistical analysis of HRQL data. Various simple and complex imputation techniques and statistical methods have been evaluated to deal with missing at random or missing not at random HRQL data. I used simulations t

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