Titlebook: Spirochete Biology: The Post Genomic Era; Ben Adler Book 2018 Springer International Publishing AG, part of Springer Nature 2018 Lyme dise

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Colonic Spirochetes: What Has Genomics Taught Us?,and these variously colonise the large intestines of different species of birds and animals, including humans. Scientific understanding of the physiology and molecular biology of . spp. remains very limited compared with that of other pathogenic spirochetes, and there are few descriptions of success

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Toolbox of Molecular Techniques for Studying , Spp.,ions. However, there are still no practical tools for routine genetic manipulation of pathogenic . strains, slowing down advances in pathogenesis research. This review summarizes the status of the molecular genetic toolbox for . species and highlights new challenges in the nascent field of . genetics.

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0070-217X advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology..978-3-030-07821-8978-3-319-89638-0Series ISSN 0070-217X Series E-ISSN 2196-9965

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0070-217X encing and the development of genetic tools for the manipula.Spirochetes comprise a fascinating group of bacteria. Although diverse in terms of their habitat, ecology and infectivity for vertebrate and non-vertebrate hosts, they are often considered together because of their similar cellular morphol

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Book 2018 experts to provide essential insights into spirochete biology, with an emphasis on recent advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology..

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Gene Regulation, Two Component Regulatory Systems, and Adaptive Responses in ,and adapt to rapidly changing environmental conditions. The purpose of this chapter is to review the current understanding of the molecular basis of these essential adaptive responses, with a focus on the role of two component regulatory systems with global regulatory potential.

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