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Titlebook: Sparking Signals; Kinases as Molecular G. Baier,B. Schraven,A. von Bonin Conference proceedings 2008 Springer-Verlag Berlin Heidelberg 2008

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書(shū)目名稱Sparking Signals
副標(biāo)題Kinases as Molecular
編輯G. Baier,B. Schraven,A. von Bonin
視頻videohttp://file.papertrans.cn/874/873394/873394.mp4
概述Internationally well known experts presented their most recent findings on the fast developing kinase field.Outstanding interest for basic researchers and pharmaceutical industry
叢書(shū)名稱Ernst Schering Foundation Symposium Proceedings
圖書(shū)封面Titlebook: Sparking Signals; Kinases as Molecular G. Baier,B. Schraven,A. von Bonin Conference proceedings 2008 Springer-Verlag Berlin Heidelberg 2008
描述.Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups..
出版日期Conference proceedings 2008
關(guān)鍵詞Cellular Signalling; Drug Finding; Immune-modulation; Kinase Inhibitors; Proteomics; Translation; metaboli
版次1
doihttps://doi.org/10.1007/978-3-540-73501-4
isbn_softcover978-3-642-09262-6
isbn_ebook978-3-540-73501-4Series ISSN 0947-6075
issn_series 0947-6075
copyrightSpringer-Verlag Berlin Heidelberg 2008
The information of publication is updating

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e university is a complex phenomenon to study multifactorial reasons for intervening in it. This exploratory study can give some guidance to universities not copy a system, but that adapt best practices to their regional needs, academic infrastructure and economic investments and to obtain optimal r
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M. Bantscheff,C. Hopf,U. Kruse,G. Drewese university is a complex phenomenon to study multifactorial reasons for intervening in it. This exploratory study can give some guidance to universities not copy a system, but that adapt best practices to their regional needs, academic infrastructure and economic investments and to obtain optimal r
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M. Koziczak-Holbro,C. Joyce,A. Glück,B. Kinzel,M. Müller,H. Gramnts that are used to express the linear and angular deformations of the compliant elements. Then, the two algorithms are coupled in an optimization problem that intend to determine the value(s) of the independent kinematic parameter(s) for which the minimum value of the static equation is reached.
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