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Titlebook: Skin Cancer after Organ Transplantation; Eggert Stockfleth,Claas Ulrich Book 2009 Springer-Verlag US 2009 carcinoma.cutaneous malignancy.e

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發(fā)表于 2025-3-21 17:38:11 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Skin Cancer after Organ Transplantation
編輯Eggert Stockfleth,Claas Ulrich
視頻videohttp://file.papertrans.cn/869/868252/868252.mp4
概述There is an emerging need for a high-grade scientific and clinical book related to chronic immunosuppression in transplant patients (more than 1,000,000 world wide).Provides an answer on the dramatica
叢書名稱Cancer Treatment and Research
圖書封面Titlebook: Skin Cancer after Organ Transplantation;  Eggert Stockfleth,Claas Ulrich Book 2009 Springer-Verlag US 2009 carcinoma.cutaneous malignancy.e
描述.Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude) are strongly related with the increased skin cancer incidence...The increasing incidence of non-melanoma skin cancer, paralleling a prolonged survival of patients after organ transplantation, represents a significant reason for morbidity and long-term morbidity in organ transplant recipients worldwide. The incidence of non-melanoma skin cancer in liver-, kidney- and heart transplant recipients varies from 1.5 to 22 %, 2 to 24 % and 6 to 34 % after < 5 years post transplant. Ultraviolet radiat
出版日期Book 2009
關(guān)鍵詞carcinoma; cutaneous malignancy; epidemiology; immunosuppression; morbidity; organ transplantation; pathop
版次1
doihttps://doi.org/10.1007/978-0-387-78574-5
isbn_softcover978-1-4419-4616-4
isbn_ebook978-0-387-78574-5Series ISSN 0927-3042 Series E-ISSN 2509-8497
issn_series 0927-3042
copyrightSpringer-Verlag US 2009
The information of publication is updating

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0927-3042 an 1,000,000 world wide).Provides an answer on the dramatica.Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via inductio
地板
發(fā)表于 2025-3-22 07:23:42 | 只看該作者
Molecular Events in Skin Cancerf the tumor lesions occur in sun-exposed skin areas and contain UV signature mutations [1, 2]. However, some tumors are located in sun-protected body areas, indicating other factors involved in carcinogenesis.
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Skin Immune Systemr of the epidermis (stratum corneum). In addition to its function as a barrier against potentially harmful outside effects, the skin also serves to maintain the homeostasis of the “milieu intùrieure” by preventing desiccation.
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Photocarcinogenesis – DNA Damage and Gene Mutations people are clearly most susceptible to these sunburn reactions. Although these dramatic reactions may leave a different impression, it appears that the skin is quite well adapted to the persistent UV challenge in its natural environment – even the excessive reactions may be considered part of a formidable adaptation.
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