Titlebook: Single-molecule Studies of Proteins; Andres F. Oberhauser Book 2013 Springer Science+Business Media New York 2013

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,AFM Visualization of Protein–DNA Interactions,described and recommendations for the selection of the appropriate methodology are provided. Studies of sequence-specific and non-sequence-specific DNA-binding proteins are limited to a few examples with a focus on recent publications. The AFM studies of complexes of DNA with architectural proteins

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Single-Molecule Studies of Amyloidogenic Proteins, these methods have been applied to the exploration of the structure, mechanics, and mechanically driven conformational changes of amyloidogenic protein systems as well. Amyloidogenic proteins are a rich and diverse group of molecules capable of forming amyloid fibrils, and many of them are implicat

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Individual Proteins Under Mechanical Stress: Lessons from Theory and Computer Simulations,Motivated by single-molecule pulling studies that probe the mechanical response of proteins and other biomolecules, this chapter introduces essential theoretical ideas needed to understand how the dynamics and thermodynamics of proteins are affected by mechanical stress. Various computational approa

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