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Titlebook: Simian Immunodeficiency Virus; Norman L. Letvin,Ronald C. Desrosiers Book 1994 The Editor(s) (if applicable) and The Author(s), under excl

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11#
發(fā)表于 2025-3-23 09:57:31 | 只看該作者
Pathology of Simian Immunodeficiency Virus Induced Disease,tives to the human immunodeficiency virus (HIV; C. etal. 1987; F. et al. 1987; H. et al. 1989). In their natural hosts, which include sooty mangabeys (.; F. et al. 1986; L. et al. 1986), African green monkeys (.; D. et al. 1988; K. et al. 1985), mandrills .; T. et al. 1988), white-crowned mangabeys
12#
發(fā)表于 2025-3-23 16:27:14 | 只看該作者
SIVsmmPBj14: An Atypical Lentivirus,cy virus (HIV), the most relevant model is infection of macaque monkeys with simian immunodeficiency viruses (SIVs). In various macaque species the majority of SIV isolates exhibit a pathogenicity which varies from development of AIDS-like disease and death within 6–12 months, such as SIV. (Z. et al
13#
發(fā)表于 2025-3-23 20:39:57 | 只看該作者
Conserved Framework of Envelope Glycoproteins Among Lentiviruses,the cell membrane with cellular receptors, they membrane fusion to allow virus entry, and they constitute a major the immune response. In the case of HIV-1, as well as that lentiviruses, comparisons of amino acid sequences among variou isolates have shown that envelope glycoproteins consist of a suc
14#
發(fā)表于 2025-3-24 02:13:19 | 只看該作者
15#
發(fā)表于 2025-3-24 05:04:39 | 只看該作者
Comparison of Regulatory Features Among Primate Lentiviruses,t al. 1984; L. et al. 1984; C. et al. 1986). Since that time, besides the human immunodeficiency viruses (HIV-1 and HIV-2), molecular isolates of simian immunodeficiency viruses (SIVs; D. 1990), as well as related viruses in cattle, cats, sheep, and goats, have been obtained. For HIVs and SIVs, exte
16#
發(fā)表于 2025-3-24 08:13:33 | 只看該作者
17#
發(fā)表于 2025-3-24 14:05:28 | 只看該作者
CD4+ T Cell Responses to Simian Immunodeficiency Virus,ze endogenous antigen in association with MHC class I molecules and display cytotoxic activity against infected or peptide-pulsed target cells. Although these cytotoxic T lymphocytes (CTL) have usually been described following infection with viruses or intracellular bacteria, they can also be induce
18#
發(fā)表于 2025-3-24 17:43:57 | 只看該作者
The SIVmac Specific Cytotoxic T Lymphocyte Response in the Acutely Infected Rhesus Monkey,ne responses that block initial virus spread are likely to be central mechanisms for containing HIV infections. It is therefore important to elucidate the virologic and immunologic events that occur immediately following HIV infection. However, since the acutely infected person comes to clinical att
19#
發(fā)表于 2025-3-24 21:57:31 | 只看該作者
Envelope Sequence Variation, Neutralizing Antibodies, and Primate Lentivirus Persistence, the primary neutralizing antibody response of the host is directed at linear versus complex epitopes or to V3 versus non-V3 determinants. Neutralization escape mutants appear to arise during the course of infection of single individuals, but the variable regions primarily responsible for this escap
20#
發(fā)表于 2025-3-25 00:21:18 | 只看該作者
Towards a Vaccine Against AIDS: Lessons from Simian Immunodeficiency Virus Vaccines,therapeutic approaches could be assessed. A wide range of mammals, including several species of non-human primates, were inoculated with strains of HIV-1 (G. et al. 1986). It soon appeared that only chimpanzees and gibbon apes were susceptible to infection by HIV-1. However, their use in AIDS resear
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