Titlebook: Sex Steroids and Bone; Reinhard Ziegler,Johannes Pfeilschifter,Matthias B Conference proceedings 1994 Springer-Verlag Berlin Heidelberg 19

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0947-6075 tment ofbone loss in theelderly. This book contains the proceedings of the ScheringWorkshop on "Sex Steroids and Bone." The various chaptersbyleading experts give and overall view of current knowledgeon thecontrol of bone hemostasis by sex steroids and newideas on how this controlcould be exerted. I

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The Effect of Sex Steroids on Calciotropic Hormones In Vivo,Naveh-Many and Silver 1990). In contrast, calcitonin gene expression is not regulated by calcium in vivo (Rodriguez et al. 1991). At the level of secretion, calcium is the major regulator for both PTH, inversely, and calcitonin, directly.

Ligneous

Effects of Estrogen on Growth Factors in Bone,rovided clearcut clues to the mechanisms by which estrogen exerts its effects on bone. Data suggest that estrogen may act on bone by several mechanisms, either directly through estrogen receptors, indirectly through other cells besides bone cells, and in concert with other factors and hormones such as the progesterones.

情節(jié)劇

Estrogens, Cytokines, and Bone Metabolism,n which osteoclasts adhere to bone and subsequently remove it by acidification and proteolytic digestion. After osteoclasts have left the resorption site, osteoblasts invade the area and begin the process of new bone formation by secreting osteoid (a matrix of collagen and other proteins), which is eventually mineralized into new bone.

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The Rat as an Animal Model of Postmenopausal Bone Loss,ctures in 1.3 million people 45 years and older [1]. The societal cost of managing osteoporosis has been estimated at over 7 billion dollars per year [2]. The price tag will continue to increase if effective measures are not developed to identify those at risk and prophylactic or therapeutic measures instituted.

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Conference proceedings 1994kshop and editors of thisvolumehope that it will contribute to a betterunderstanding of the role of sex steroids in bone and thuspave the way for a better experimental approach instudyingdrug effects on bone with the ultimate goal of improvingtherapy in bone diseases.

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0947-6075 of the workshop and editors of thisvolumehope that it will contribute to a betterunderstanding of the role of sex steroids in bone and thuspave the way for a better experimental approach instudyingdrug effects on bone with the ultimate goal of improvingtherapy in bone diseases.978-3-662-03045-5978-3-662-03043-1Series ISSN 0947-6075