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Titlebook: Serotonin Receptor Technologies; Wolfgang Blenau,Arnd Baumann Book 2015 Springer Science+Business Media New York 2015 5-HT receptor subtyp

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書目名稱Serotonin Receptor Technologies
編輯Wolfgang Blenau,Arnd Baumann
視頻videohttp://file.papertrans.cn/866/865489/865489.mp4
概述Includes cutting-edge methods and protocols involving the serotonergic system.Provides vital details essential for reproducible results.Contains key notes and implementation advice from the experts
叢書名稱Neuromethods
圖書封面Titlebook: Serotonin Receptor Technologies; Wolfgang Blenau,Arnd Baumann Book 2015 Springer Science+Business Media New York 2015 5-HT receptor subtyp
描述.Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na.+.-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. .Serotonin Receptor Technologies. describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular .Neuromethods. series, chapters include the kind of detail and practical advice that ensures successful results in the lab..Authoritative and convenient, .Serotonin Receptor Technologies. serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and
出版日期Book 2015
關(guān)鍵詞5-HT receptor subtypes; Central nervous system (CNS); Drug action; Na+-dependent serotonin transporter;
版次1
doihttps://doi.org/10.1007/978-1-4939-2187-4
isbn_softcover978-1-4939-5562-6
isbn_ebook978-1-4939-2187-4Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightSpringer Science+Business Media New York 2015
The information of publication is updating

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Novel Approaches to Serotonin Receptor Interaction Studies participate in a wide range of signal transduction pathways. Alterations of their activities often occur in pathological and psychopathological disorders. Therefore, these receptors determine major targets for drug discovery. Currently, the concept of GPCR oligomerization has become widely accepted
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Organotypic Slices and Biolistic Transfection for the Study of Serotonin Receptor Function in CNS Neadvantages of isolated in vitro experimental preparations with preservation of key aspects of the neuronal anatomy and physiology seen in whole animals. Acutely prepared slices have proven very useful for the study of serotonin (5-HT) signaling in the CNS, and neuronal signaling in general. The usef
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The Murine Serotonin Syndrome and the 5-HT1A Receptor: Behavioral Effects and Hypothermiae agonists at 5-HT receptors. The symptoms include mental state alterations (e.g., agitation, confusion), neuromuscular excitation (e.g., myoclonus, tremor), and autonomic dysregulation (e.g., hyperthermia, tachycardia). Similar symptoms can also be induced in rodents, especially in rats, whereas in
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5-HT4 Receptor Subtype, β-Arrestin Level, and Rapid-Onset Effects of Antidepressant Drugsspects of the disease. The use of exogenously administered corticosterone (CORT model) can mimic the effects of a chronic stress and has been validated as an animal model to study disease states displaying some hallmark characteristics of anxiety and depression observed in patients..Recently, we hav
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