Titlebook: Serological Cancer Markers; Stewart Sell Book 1992 Springer Science+Business Media New York 1992 antigen.breast cancer.cancer.carcinoma.ce

instructive

TAG-72 as a Tumor Marker,ma metastasis (Colcher et al., 1981). The B72.3-reactive antigen has subsequently been purified and characterized and has been termed TAG-72, for tumor-associated glycoprotein (Johnson et al., 1986). As a result of the purification of TAG-72, a second generation of anti-TAG-72 MAbs has been generate

BORE

CA 125,(Bast et al., 1981), there has been extensive investigation of the potential clinical value of CA 125 determination. In this chapter we will review the present status of CA 125 determination for screening and management of Gynecologic malignancies and will as summarize the biochemistry of CA 125 and

exceptional

BIAS

Prostate-Specific Antigen,na et al., 1989; Killian and Chu, 1990). It should be noted that PSA is not a neoantigen of prostate cancer or a prostate cancer specific antigen; rather, it is expressed equally, but exclusively, by normal, benign hyperplastic and cancerous prostate glands (Wang et al., 1979; Papsidero et al., 1981).

絕食

DU-PAN-2, A Clinically Useful Mucin Marker of Differentiation of Pancreatic and Other Ductal Cells lated to tumor invasion and compression of the common bile duct. Tumor involvement in the head of the pancreas is found in 80–90% of patients with exocrine pancreatic tumors. The remaining 10–20% of patients have tumors in the tail of the pancreas and are not likely to have early jaundice because of slight involvement of the biliary duct system.

搏斗

TAG-72 as a Tumor Marker,d and characterized (Muraro et al., 1988); because the TAG-72 was obtained from a human colon cancer xenograft (LS-174T), these second-generation MAbs have been given the designation CC (i.e., CC49 and so on).

floaters

Glycoamines: Structural-Functional Characterization of a New Class of Human Tumor Markers,nown to be elevated in blood plasma from animals and humans with a wide range of malignant neoplasms and leukoses (Glinsky, 1988a,b, 1989). It is important that at least in some forms of human malignant tumor the level of glycoamines is already increased at the early stages of the disease.

Exterior

Mucin-Like Cancer-Associated Antigen (MCA) as Available Circulating Tumor Marker for Breast Cancer,1984; Hilkens et al., 1985; Iacobelli et al., 1985; White et al., 1985; Bray et al., 1987; Cohen et al., 1987). The different epitopes are usually carried by mucinous substances, which belong to a polymorphic family of glycoproteins produced by the glandular mucinous epitelia ?Smets and Van Beek, 1984; Feizi, 1985; Hakomori, 1989).

nurture

針葉

Carcinoembryonic Antigen,an half of the mol mass and 28 potential N-linked glycosylation sites on CEA have been identified (Beauchemin et al., 1987; Oikawa et al., 1987a). CEA, an oncodevelopmental human tumor marker, is associated with carcinomas, especially those from the gastrointestinal tract (Shively and Beatty, 1985; Sikorska et al., 1988).