Titlebook: Role of RNA and DNA in Brain Function; A Molecular Biologic Antonio Giuditta,Barry B. Kaplan,Claire Zomzely-Ne Book 1986 Springer Science+B

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Regulation of Expression of the Human Proenkephalin Gene in Heterologous Cell Systemsenkephalin gene into the genome of a mouse pituitary cell line (AtT-20) results in the accurate transcription of the proenkephalin gene. Protein analysis revealed that the translated proenkephalin is accurately cleaved to mature Met-enkephalin peptides. A second gene transfer approach used to study

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The Regulation of Proopiomelanocortin Gene Expression by Estrogen in the Rat HypothalamusMC cDNA probe to measure the levels of POMC mRNA in the arcuate region of the brain in ovariectomized female rats with and without estrogen replacement. Our results show that estrogen causes a time dependent decrease in POMC mRNA of approximately 40% in rats ovariectomized for 2 wk. Preliminary stud

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DNA Analysis of Duchenne and Becker Muscular Dystrophies the same region of the human X chromosome at Xp21. Several restriction fragment length polymorphisms bridging the loci have been characterized which permit the carrier detection and antenatal diagnosis of these disorders in informative families. Methods being developed to identify the defects at th

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The Effect of Trisomy-21 (Down’s Syndrome) on Brain Transcriptionor a 68 kD microtubule-associated protein (68K MAP). This protein, whose gene thus putatively maps to chromosome 21, is a component of synaptic structures and membranes. An imbalance in its synthesis during brain development could contribute to the abnormal brains characteristic of Down’s syndrome.

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978-1-4612-9427-6Springer Science+Business Media Dordrecht 1986

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Role of RNA and DNA in Brain Function978-1-4613-2321-1Series ISSN 0897-3946

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Topics in the Neuroscienceshttp://image.papertrans.cn/r/image/831550.jpg

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