Titlebook: Role of Apoptosis in Infection; Diane E. Griffin Book 2005 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr

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Apoptotic Cells at the Crossroads of Tolerance and Immunity,rogenic signals. On the other hand, dendritic cells can efficiently process and present antigens from pathogen-infected apoptotic cells to T cells. In this review, we discuss how apoptotic cells manipulate immunity through interactions with dendritic cells.

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Poliovirus, Pathogenesis of Poliomyelitis, and Apoptosis,he development of new animal and cell models has allowed the key steps of the pathogenesis of poliomyelitis to be investigated at the molecular level. In particular, it has been shown that PV-induced apoptosis is an important component of the tissue injury in the CNS of infected mice, which leads to

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Neuronal Cell Death in Alphavirus Encephalomyelitis,eningitis, and encephalomyelitis. Sindbis virus (SINV) is the prototype alphavirus, causes encephalomyelitis in mice, and provides a model system for studying the pathogenesis of alphavirus-induced neurological disease. Major target cells for SINV infection in the central nervous system (CNS) are ne

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The Role of Host Cell Death in , Infections,ease produces widespread destruction of the intestinal mucosa. . strains can also disseminate from the intestine and produce serious, sometimes fatal infections with considerable cytopathology in a number of systemic organs. A combination of bacterial genetic and cell biology studies have shown that

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