Titlebook: Rodent Quality Control: Genes and Bugs; Monitoring Health an Fernando Benavides,Axel Kornerup Hansen Book 2024 The Editor(s) (if applicable

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Statistical Aspects of Health Monitoring in Rodents,ion of animals that it is reasonable to assume, that this specific agent will infect in the colony, and the sensitivity of the assay, i.e., how the fraction of the infected animals are likely to become positive in the assay. In smaller colonies, the size of the colony also has an impact on the sample size

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Health Monitoring Programmes and International Standards, some advice for the shipping of samples. The importance of comprehensive health reporting including test methods applied and the handling of unexpected or positive test results are stressed, and some suggestions are made on what to do in the case of an infectious outbreak. Finally, the authors give

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Bacteria and Bacterial Diagnostics,d of preliminary propagation of the agent in cell culture. A major limitation of 16S rRNA gene sequence-based methods for identification including PCR is that some species cannot be separated, for instance, within . The same problem is relevant for MALDI-TOF MS, and in such cases, whole genome seque

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Laboratory Animal Pathology in Relation to Spontaneous Infections, handling, fixation, processing and staining are covered. At the end of this chapter, different histochemical and molecular in situ identification techniques are addressed in both text and illustrations, which are followed by the histological demonstration of different examples of spontaneous infect

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2730-7859 and guides the reader in monitoring the animals’ health status through application of current diagnostic methods.??..?..This book adresses researchers, technicians and zookeepers working in laboratory rodent facilities..978-3-031-59105-1978-3-031-59103-7Series ISSN 2730-7859 Series E-ISSN 2730-7867