Titlebook: Reviews on New Drug Targets in Age-Related Disorders; Paul C. Guest Book 2020 The Editor(s) (if applicable) and The Author(s), under exclu

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The Effects of Parabiosis on Aging and Age-Related Diseases,searchers to ask whether or not transmissible factors in the blood of one parabiont have physiological effects on its partner. In other words, parabiosis allows researchers to explore whether circulating factors in the bloodstream can alter tissue function. Heterochronic parabiosis, the pairing toge

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Skeletal Muscle Aging Atrophy: Assessment and Exercise-Based Treatment,In association, muscle strength and functionality also decrease. The geriatric assessment allows knowing the baseline situation of the patients, determines the impact of diseases, and defines specific treatments. There are various tools to evaluate the health condition of older people. These tools i

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Polyphenols as an Effective Therapeutic Intervention Against Cognitive Decline During Normal and Paong the polyphenols, berry phenolics have extensive beneficial effects because of their antioxidant and anti-inflammatory properties. Long-term consumption of grapes results in accumulation of polyphenols in the brain, which modulates cell-signalling pathways and neutralises the redox imbalance in t

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,Early Diagnosis and Targeted Treatment Strategy for Improved Therapeutic Outcomes in Alzheimer’s Di fact that Alzheimer’s disease is a heterogeneous disorder caused by person-to-person differences in genetic background, epigenetic profiles, environmental triggers, or the presence of other diseases. Furthermore, most Alzheimer’s disease patients are diagnosed in the middle to late stages of the il

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Targeting ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Cancer,cer cells upon different drug treatments and gene modifications. The mechanisms and consequences involved in ROS-mediated crosstalk between apoptosis and autophagy are extremely complex in cancer cells. Here, we mainly discuss the closely linked relationship between ROS levels, autophagy, and apoptosis in cancer therapy.