Titlebook: Reviews of Physiology, Biochemistry and Pharmacology 147; Book 2003 The Editor(s) (if applicable) and The Author(s), under exclusive lice

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Reviews of Physiology, Biochemistry and Pharmacology 147978-3-540-36622-5Series ISSN 0303-4240 Series E-ISSN 1617-5786

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https://doi.org/10.1007/978-3-540-36622-5Nicotinic Acetylcholine Receptors; Peroxisome; Protein Aggregation; Protein transport; Redox; TolC; Acetyl

PATRI

Curmudgeon

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Channel-tunnels: outer membrane components of type I secretion systems and multidrug efflux pumps orane component. Its remarkable conduit-like structure, protruding 100 ? into the periplasmic space, reveals how both systems are capable of transporting substrates across both membranes directly from the cytosol into the external environment. Proteins of the channel-tunnel family are widespread with

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