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Titlebook: Retinal Degenerations; Mechanisms and Exper Matthew M. LaVail,Joe G. Hollyfield,Robert E. Ande Conference proceedings 2003 The Editor(s) (i

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發(fā)表于 2025-3-21 17:23:46 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Retinal Degenerations
副標(biāo)題Mechanisms and Exper
編輯Matthew M. LaVail,Joe G. Hollyfield,Robert E. Ande
視頻videohttp://file.papertrans.cn/830/829206/829206.mp4
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Retinal Degenerations; Mechanisms and Exper Matthew M. LaVail,Joe G. Hollyfield,Robert E. Ande Conference proceedings 2003 The Editor(s) (i
描述The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration..Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
出版日期Conference proceedings 2003
關(guān)鍵詞Diabetes; Stress; death; epidemiology; etiology; eye; macular degeneration; neurons; receptor; retina; retinob
版次1
doihttps://doi.org/10.1007/978-1-4615-0067-4
isbn_softcover978-1-4613-4909-9
isbn_ebook978-1-4615-0067-4Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

書目名稱Retinal Degenerations影響因子(影響力)




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發(fā)表于 2025-3-21 22:40:07 | 只看該作者
An Integrated Genetic Approach to Identify Candidate Genes for Human Chromosome 6q-Linked Retinal D.Online Mendelian Inheritance in Man (OMIM).. Despite recent efforts to discover novel genes by analyzing increasingly greater volumes of information arising from human genomic sequence data organization and expression studies, the disease genes for less than one-half of these conditions have at pre
板凳
發(fā)表于 2025-3-22 01:23:51 | 只看該作者
Comparing Rod and Cone Function with Fundus Autofluorescence Images in Retinitis Pigmentosa, of AF may indicate photoreceptor cell death leading to RPE atrophy. However, the presence of abnormal AF suggests continuing metabolic demand possibly representing compromised RPE function before cell death.
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發(fā)表于 2025-3-22 07:21:41 | 只看該作者
A Modified Protocol for the Assessment of Visual Function in Patients with Retinitis Pigmentosa,l field test (VF) using Humphrey (10-2), 4) Color vision using Mollon-Reffin `minimalist’ test and 5) Subjective visual function questionnaire testing near and global perceived visual function respectively..The phase I results shows that correlation of measured visual function to patient’s subjectiv
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發(fā)表于 2025-3-22 11:39:25 | 只看該作者
,Prenatal Human Ocular Degeneration Occurs in Leber’s Congenital Amaurosis, cone rod homeobox (Crx) transcription factor (LCA3), photoreceptor-pineal gene-specific aryl interacting-like protein 1 (AILP1) (LCA4), retinitis pigmentosa GTPase regulator interacting protein (RPGRIP1) (LCA5) and Crumbs homologue 1 (CRB1). Additional genes involved in this group of diseases remai
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Progressive Pathways in Age-Related Macular Degeneration,issues is essential for successful therapeutic intervention of AMD. We propose that receptor-mediated cellular activation by advanced glycation end (AGE) products, a major contributor to progressive tissue damage in other aging disorders, may also contribute significantly to progressive damage in AM
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發(fā)表于 2025-3-23 08:11:25 | 只看該作者
Usher Syndrome: Correlation between Visual Field Size and Maximal ERG Response B-Wave Amplitude,ential of any given retina, as it already encompasses the gain of the visual response performed intraretinally by the bipolar cells. In addition, since both the rod-and cone-driven pathways can contribute to the detection of the test targets used conventionally to delimit visual fields with the Gold
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