Titlebook: Reprogramming Microbial Metabolic Pathways; Xiaoyuan Wang,Jian Chen,Peter Quinn Book 2012 Springer Science+Business Media Dordrecht 2012 F

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Tunable Promoters in Synthetic and Systems Biologyeeded to quantitatively analyze the behavior of biological systems while the efficient engineering of artificial gene networks is central in synthetic biology. A number of tools exist to manipulate the steps in between gene sequence and functional protein in living cells, but out of these the most s

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Analysis of , Promoters and Their Applicationsy influence levels of gene expression, they have become powerful tools in metabolic engineering. Methods for their localization used in . and techniques for the analysis of their function are described in this review. . promoters can be classified according to the respective σ factors which direct R

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Production of Fumaric Acid by Fermentationrocesses. So far, using . strains, the best fermentations reported have achieved a fumaric acid titer of 126 g/L with a productivity of 1.38 g L. h. and a yield on glucose of 0.97 g/g. This requires pH control, aeration, and carbonate/CO. supply. Limitations of the used strains are their pH toleranc

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Metabolic Engineering of Microorganisms for Vitamin C Production the Reichstein method, biotechnological production of vitamin C is an attractive approach due to the low cost and high product quality. In this chapter, biosynthesis of vitamin C, including one-step fermentation processes and two-step fermentation processes are discussed and compared. Furthermore,

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Manipulation of , Carbon Storage Pathways to Produce Useful Bio-Based Productscellularly in the form of polyhydroxyalkanoate. Many aspects of .make it a good candidate for use in biotechnological production of polyhydroxyalkanoate and other bio-based, value added compounds. Manipulation of the organism’s carbon flux is a cornerstone to success in developing it as a biotechnol

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Monitoring Microbial Diversity of Bioreactors Using Metagenomic Approachesfficient industrial processes for the production of bioproducts. This chapter will provide an overview of bioreactors and metagenomic technologies to help the reader understand microbial communities, interactions, and functions in bioreactors.