Titlebook: Regulation of Cytokine Gene Expression in Immunity and Diseases; Xiaojing Ma Book 2016 The Editor(s) (if applicable) and The Author(s), un

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Regulation of Interleukin-23 Expression in Health and Disease,omotes the protection of the host against mucosal pathogens through the induction of IL-17 and related cytokines by lymphoid cells. Preclinical disease models and association studies in humans have also clearly demonstrated the implication of IL-23 signalling pathway in inflammatory diseases. Indeed

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0065-2598 th healthy physiological conditions and in pathological situ.This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathologi

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Regulation of Interleukin-23 Expression in Health and Disease, Herein, we review our current understanding of IL-23 regulation at the transcriptional and post-transcriptional levels. We discuss the relevance of these findings in the context of infection, chronic inflammation and cancer.

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Regulation of IL-4 Expression in Immunity and Diseases,at several levels, including signaling pathways, transcription factors, epigenetic modifications, microRNA, and long noncoding RNA. This chapter will review in detail the molecular mechanism regulating the cell type-specific expression of IL-4 in physiological and pathological type 2 immune responses.

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cally built to help determine (calculate/forecast) the impact of . on .. These models have many names, including algebraic, mathematical, deterministic, analysis, and decision model. Speadsheet models are usually built in this way. They rarely use probabilities, and usually reply on simple, direct,

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