Titlebook: Regenerative Medicine; From Protocol to Pat Gustav Steinhoff Textbook 2013Latest edition Springer Science+Business Media Dordrecht 2013 Bio

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Human Embryonic Stem Cellshe name indicates, derived from the inner cell mass of pre-implantation stage blastocysts at day 5–7 post fertilisation. These cells possess qualities such as pluripotency and a seemingly limitless capacity to proliferate . in their undifferentiated state. Embryonic stem cells were first derived fro

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Induced Pluripotent Stem Cells to convert somatic cells to a pluripotent state. Direct reprogramming with defined factors, is the newest of these approaches. This method requires just a few genes, and it also has a great reproducibility. Applying this method to humans seems to open the door to cell transplantation therapy withou

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Spermatogonial Stem Cellsgenesis in the male as they can only differentiate into sperms within the testicular niche. The long-term culture of SSCs without loss of their properties provides the opportunity to develop therapeutic strategies and re-initiate spermatogenesis for the patients who become infertile after cancer the

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Hematopoietic Stem Cellsde array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will one day be useful in the treatment of a whole host of diseases that involve cellular loss. In this chapter we describe how hematopoietic stem cells can

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Cardiovascular Stem Cellsation, congestive heart failure is the rising health problem. At present, heart transplantation remains the only curative treatment for end stage heart failure. The discrepancy between demand and supply of donor organs does not fill the clinical need. This explains the huge effort made in the field

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Neural Stem Cells cells are consumed during embryonic development, a subpopulation persists in specialized regions of the adult mammalian brain where addition of cells, notably neurons, continues throughout life. The significance and physiological role of adult neurogenesis are still debated but it is generally beli

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Gastro Intestinal Stem Cellsdentified as esophageal, gastric, intestinal, hepatic and pancreatic stem cells. Intestinal stem cells are most extensively studied in mouse models. In the small intestine stem cells reside at the base of the crypt at the 4th position and give rise to all cell lineages of the crypt, while in the lar

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Cancer Stem Cellsmancy that leads to cancer recurrence after therapy presents formidable obstacles through severely limiting the successful treatment outcomes for majority of cancers. Significant advances made recently in the cancer stem cell (CSC) biology field have provided new insights into cancer biology that ar