Titlebook: Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology; Scientific and Clini Mohammad Resa Nowrousian Book 2008Latest edition Spring

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Pathophysiology of anemia in cancer,ematologic malignancies. Cancer is the cause of anemia in 19% of cases of ACD (.). CRA is often associated with advanced stages of disease, and usually worsens during chemotherapy or radiotherapy, leading to a high proportion of patients requiring red blood cell (RBC) transfusions (., .; .). Chemoth

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Pharmacology, pharmacokinetics and safety of recombinant human erythropoietin preparations,ention. The decision to transfuse is usually based on the severity of the clinical symptoms of hypoxia, and on the patient’s age and co-morbidity. The transfusion of allogeneic blood components is associated with the risk of immunologic reactions and of bacterial or viral infection. In addition, rep

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,rhEPO in anemic patients with solid tumors and chemotherapy — efficacy and safety,Hb) levels less than 11 g/dl rose from 17% before the first cycle, to 38% by the sixth cycle of chemotherapy, despite transfusions in 33% of patients. In a large European cancer anemia survey (ECAS) including 8,470 patients on chemotherapy, anemia (Hb < 12g/dl) was reported to occur in 62 to 88% of

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M. R. Nowrousianearn. There is a rich set of problems that are well-suited to this type of tool. Most of the systems described in this book have been developed with these relatively simple tools..Larger and more complex applications seem to require more sophisticated tools. Frame-based systems provide a growth path

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