Titlebook: Receptor Purification; Volume 1 Receptors f Gerald Litwack Book 1990 Springer Science+Business Media New York 1990 G proteins.Vitamin D.att

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,μ-Opioid Receptor,eptors were reported by several independent investigators, in a ligand binding study in brain membranes (.; .; .; .). The study of opioid receptors was accelerated by the discovery of endogenous opioids, such as enkephalins (.), β-endorphin, dynorphin, and their related peptides (.; Yamashiro and .)

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The Neurotensin Receptor from Mammalian Brain,m (.) and in the gastrointestinal tract (.). A number of pharmacological, biochemical, and histochemical data suggest that neurotensin works as a neurotransmitter or neuromodulator in the brain (.) and as a hormone in the periphery (.). Both modes of action imply as a first step the selective intera

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The Luteinizing Hormone/Human Chorionic Gonadotropin Receptor of Testis and Ovary,ith trophic hormone and coupling elements in the membrane facilitates the understanding of biochemical mechanisms that control the reproductive functions and is of general value to gain insight on the mechanisms of action of glycoprotein hormones.

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Thyrotropin Receptor,existence of a glycolipid (Fig. 1) that can modify the binding properties of this glycoprotein, as well as act as a coupler of the high affinity binding site to G proteins related to adenylate cyclase complex, has also been argued (.; .); its role is more controversial. No consensus currently exists

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Thyrotropin Receptor Purification, follicular cells (.; .; .; .; .). Binding initiates a sequence of processes (including stimulation of adenylate cyclase, production of cyclic AMP and activation of protein kinases, stimulation of phospholipid turnover and mobilization of intracellular calcium) that are presumed to mediate the bioef

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Ligand- and Antibody-Affinity Purification of the Epidermal Growth Factor Receptor, the EGF receptor as a model system. Binding of EGF to its receptor initiates a cascade of cellular events, presumably through stimulation of its intrinsic tyrosine-specific protein kinase activity, which culminate in DNA synthesis and cell division (. .). Studies using purified EGF receptor have he