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Titlebook: Receptor Binding Techniques; Anthony P. Davenport Book 2012Latest edition Springer Science+Business Media, LLC 2012 G-protein-coupled rece

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書目名稱Receptor Binding Techniques
編輯Anthony P. Davenport
視頻videohttp://file.papertrans.cn/824/823543/823543.mp4
概述Updates the previous edition with cutting-edge content.Provides step-by-step detail essential for reproducible results.Contains key notes and implemenatation advice from the experts.Includes supplemen
叢書名稱Methods in Molecular Biology
圖書封面Titlebook: Receptor Binding Techniques;  Anthony P. Davenport Book 2012Latest edition Springer Science+Business Media, LLC 2012 G-protein-coupled rece
描述.A broad definition of a receptor is a specialized protein on or in a cell that recognizes and binds a specific ligand? to undergo a conformational change, leading to a physiological response or change in cell function.? A ligand can be an endogenous neurotransmitter, hormone, paracrine/autocrine factor, or a synthetic drug that may function as an agonist or antagonist. The third edition of? .Receptor Binding Techniques .expands upon the methods and techniques used for studying receptors in silico, in vitro and in vivo. Comprehensive chapters describe how to use online resources for experimental research such as prediction of receptor-ligand interactions and mine the IUPHAR receptor database. Classical techniques of radioligand binding, quantitative autoradiography and their analyses are complemented by the use of? immunocytochemistry? for the cellular localization of receptor protein and hybridization to detect receptor mRNA.? Protocols using fluorescent labeled ligands are described to visualise receptors in living cells, their interaction with beta-arrestin to measure ligand-induced internalisation and? green fluorescent protein to study ?trafficking. Non-radioactive, chemilumin
出版日期Book 2012Latest edition
關(guān)鍵詞G-protein-coupled receptors; Immunocytochemistry; PET scanners; Radioligand binding; anatomical distribu
版次3
doihttps://doi.org/10.1007/978-1-61779-909-9
isbn_softcover978-1-4939-5936-5
isbn_ebook978-1-61779-909-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC 2012
The information of publication is updating

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Daniel L. Bassoni,Qumber Jafri,Sunitha Sastry,Mahesh Mathrubutham,Tom S. Wehrmanand tools. I was familiar with MRP; it had been part of the required curriculum for my bachelor’s degree, plus I had some prior experience with MRP systems. However, MRP was a very new idea at Lockheed, and it was the antithesis of the philosophy behind the existing systems. My boss and mentor, Skip
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https://doi.org/10.1007/978-1-61779-909-9G-protein-coupled receptors; Immunocytochemistry; PET scanners; Radioligand binding; anatomical distribu
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978-1-4939-5936-5Springer Science+Business Media, LLC 2012
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Receptor Binding Techniques978-1-61779-909-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Receptor Databases and Computational Websites for Ligand Binding,nd computational comparisons among receptors. The Websites include databases of receptor protein and nucleotide sequences for particular classes of receptors (such as G-protein-coupled receptors and nuclear receptors) and of experimental results from receptor–ligand binding assays, as well as comput
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