Titlebook: Recent Trends in Regeneration Research; V. Kiortsis,S. Koussoulakos,H. Wallace Book 1989 Springer Science+Business Media New York 1989 Emb

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How Many Populations of Cells Occur in the Mesenchymal Blastema?owth rate. A literature survey finds no distinct subpopulations have been identified in the blastema by other criteria. Consequently, blastemal mesenchyme cells can still be validly considered as a single population.

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Production of Growth Factors by the Blastema During Limb Regeneration of Urodeles (Amphibia) on blastema cells, extraction of heparin-binding growth factors from blastemata and immunolocalization of aFGF. Our results show that both epidermal cap and blastema mesenchyme contain aFGF. This growth factor is probably involved in blastema cell proliferation during regeneration but not in the neurotrophic activity of blastemata.

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Epimorphic Regeneration and the Immune Systemof regeneration. This suggests that the nature of wounds can modulate expression of cellular immunity which, in turn, can affect mechanisms of wound repair, e.g. epimorphic regeneration vs fibroplasia and fibrosis.

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An Overview of the Historical Origin of the Nerve Influence on Limb Regeneration in 1823 was largely unsupported for 100 years. The present paper speculates on the reason for Todd’s experiment against the background of arguments of the day on the neurotrophic activity of the nervous system, derangements of which were believed to cause all the diseases of the body (Cullen, 1776;

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An Examination of Heat Shock and Trauma-Induced Proteins in the Regenerating Forelimb of the Newt, ,putation. We also examined the developmental regulation and heat inducible expression of these proteins during subsequent stages of regeneration. Both heat shock and amputation cause a decrease in total protein synthesis and the selective synthesis of 70 kD proteins. Two-dimensional gel electrophore

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C-, Proto-Oncogene Expression During Newt Limb Regenerationed .-cDNA was used as probe. Autoradiographic grains representing .-homologous RNAs were observed in cells of the thickened wound epidermis, irrespective of the layer examined. Further, mesenchymatous-like cells which form the blastema also contained multiple grains, indicating that these cells poss

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How Many Populations of Cells Occur in the Mesenchymal Blastema?ls. The labelling index of 6–13 day axolotl limb regenerates was assessed after incorporating tracer for 3–24 hours. The results indicate that the blastemal mesenchyme is never an entirely homogeneous population of proliferating cells, but that a persistent dedifferentiation of stump tissues and the

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