Titlebook: Recent Progress in the Chemical Synthesis of Antibiotics; G. Lukacs (Directeur de Recherche C.N.R.S.),M. Ohn Book 1990 Springer-Verlag Ber

chisel

小歌劇

Arb853

Actinobolin and Bactobolin: Chemical Aspects and Syntheses,uction. If the natural product is complex, because of the presence of delicate functional groups and/or myriad chiral centers, the challenge becomes virtually irresistible. If the material displays biological activity, organic chemists will succumb to the challenge, and in time, a synthesis will be

enchant

Affection

Total Synthesis of Lincomycin and Related Chemistry,f the antibiotic lincomycin. In the first part we present total syntheses of lincosamine that start from carbohydrate precursors. The D-galactose-derived aldehyde is the most frequently used synthon. In the second part, total syntheses of lincosamine from non-carbohydrate precursors are presented. T

無(wú)彈性

Synthetic Study on Man-Made Bleomycins Based on the Anticancer Mechanism of Natural Bleomycins,.-β-Hydroxy-.-histidine, a novel amino acid constituent of BLM and a pivotal amino acid for the biological activity, has been prepared based on the stereocontrolled aldol strategy using chiral 1,3-oxazolidin-2-one auxiliary. In order to study the biochemical functions of BLM, model compounds have be