Titlebook: Recent Advances in Clinical Trial Design and Analysis; Peter F. Thall Book 1995 Springer Science+Business Media New York 1995 AIDS.An?sthe

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燦爛

自由職業(yè)者

The exact analysis of contingency tables in medical research,zes are reasonably large and well balanced across the populations. For small, sparse, skewed, or heavily tied data, the asymptotic theory may not be valid. See Agresti and Yang [1] for some empirical results, and Read and Cressie [2] for a more theoretical discussion.

染色體

mutineer

headlong

Madrigal

Issues in the design and analysis of AIDS clinical trials,of clinical trial design and analysis, and the body of this chapter highlights a few of these. Before beginning, however, we consider the question of why it is necessary, or at least useful, to focus on advances in methodology for AIDS clinical trials.

nonradioactive

使害羞

The alpha spending function approach to interim data analyses,Numerous clinical trials have been conducted during this period across a wide variety of diseases, evaluating drugs, procedures, devices, and biologic materials. The fundamentals of the design, conduct, and analyses of clinical trials have been developed and refined during this period as well. One s

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