Titlebook: Recent Advances in Cell Biology of Acute Leukemia; Impact on Clinical D Wolf-Dieter Ludwig,Eckhard Thiel Conference proceedings 1993 Spring

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Clinical Significance of Cytogenetic Studies in Childhood Acute Lymphoblastic Leukemia: Experience o et al. 1986; Yunis et al. 1986; Seeker-Walker 1990), it has become evident during the last few years that their prognostic importance may be overcome by appropriate therapy (Fletcher et al. 1989; Seeker- Walker 1990; Raimondi et al. 1990).

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Chromosomal Abnormalities in Adult Acute Lymphoblastic Leukemia: Results of the German ALL/AUL Studynd immunologic parameters. In this report on chromosomal aberrations in adult ALL, some of these aspects will be touched upon within a discussion of specific chromosomal aberrations, including the possible significance of certain secondary aberrations in Ph- positive ALL.

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Detection of Residual Leukemic Cells in Adult Acute Lymphoblastic Leukemia by Analysis of Gene Rearrrangements are used as markers of clonality and thereby monoclonal lymphoid cells can be detected with an high degree of sensitivity (Korsmeyer et al. 1983; Aisenberg and Wilkes 1985; Raghavachar et al. 1986). Even in bone marrow samples considered morphologically to be free from leukemic cells, ana

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Interleukin-2-Based Immunotherapy in the Management of Minimal Residual Disease in Acute Leukemia PaCR) following induction chemotherapy, in the great majority of adult acute leukemia’s this is unfortunately short-lived, indicating that the neoplastic clone has not been eradicated by treatment. Only a minority of adults with acute leukemia’s in fact survive long. This confirms that the definition

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Conference proceedings 1993of the international workshop that we held in Berlin with a select group of scientists and clinicians involved in leukemia research was to describe the state of the art and new developments in the immunologic, cytogenetic, and molecular characterization of acute leukemias and to discuss the clinical

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