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Titlebook: RNP Particles, Splicing and Autoimmune Diseases; Johannes Schenkel Book 1998 Springer-Verlag Berlin Heidelberg 1998 Autoimmunkrankheit.RNA

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書(shū)目名稱(chēng)RNP Particles, Splicing and Autoimmune Diseases
編輯Johannes Schenkel
視頻videohttp://file.papertrans.cn/821/820225/820225.mp4
概述A practical tool for anyone working at the lab bench.Easy to follow step-by-step protocols.Background information and full practical details
叢書(shū)名稱(chēng)Springer Lab Manuals
圖書(shū)封面Titlebook: RNP Particles, Splicing and Autoimmune Diseases;  Johannes Schenkel Book 1998 Springer-Verlag Berlin Heidelberg 1998 Autoimmunkrankheit.RNA
描述The maturation of the precursors of mRNA to a functional transcript in eukaryotic cells is a complex, multistep process. It includes the formation of RNP complexes and the splicing procedure. Also, the presence of snRNA packaged as snRNP particles plays an important role in this process. In addition, snRNPs are involved in various autoimmune diseases in which autoantibodies are directed against components of these particles. .Relevant techniques to investigate RNA processing, splicing, protein-RNA complex formation and protein-RNA interactions as well as the use of autoantibodies in basic and clinical research are presented in this manual.
出版日期Book 1998
關(guān)鍵詞Autoimmunkrankheit; RNA; RNP particles (ribonucleoprotein particles); Zellkern; autoantibodies; autoantig
版次1
doihttps://doi.org/10.1007/978-3-642-80356-7
isbn_softcover978-3-642-48975-4
isbn_ebook978-3-642-80356-7
copyrightSpringer-Verlag Berlin Heidelberg 1998
The information of publication is updating

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Isolation and Immunochemical Characterization of hnRNP Particles,ort from the nucleus to the cytoplasm is a multistep process: A modified nucleotide (cap structure) is added to the 5’ end of the primary transcript, intervening sequences (introns) are spliced and the 3’ ends are polyadenylated.
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Intrinsic Fluorescence Techniques for Studies on Protein-Protein and Protein-RNA Interactions in RNterial-consuming experiments, one would like to get as much information as possible from highly sensitive techniques. Analysis by light is particularly material conserving but this technique is quite often not used to its full potential. The purpose of this chapter is to show the potential of simple
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Methods in Immunolocalization of Autoantigens,o discriminate between foreign and self antigens. The mechanisms by which this discrimination is accomplished shall not be discussed here (there are numerous excellent textbooks on immunology available). However, in autoimmune disorders this discrimination fails to a certain extent due to mechanisms
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