| 書目名稱 | RNA Therapeutics | | 副標(biāo)題 | Function, Design, an | | 編輯 | Mouldy Sioud | | 視頻video | http://file.papertrans.cn/821/820203/820203.mp4 | | 概述 | Collects in one single volume the most relevant RNA-based technologies, including ribozymes, RNA aptamers, and siRNAs, and mRNA-encoding therapeutic proteins.Features the translation of RNA-based ther | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .Central to the synthesis of proteins, the performance of catalysis, and many other physiological processes, the aberrant expression of which can be linked to human diseases including cancers, RNA has proven to be key target for therapeutics as well as a tool for therapy. In .RNA Therapeutics: Function, Design, and Delivery., expert contributors from a broad spectrum of scientific backgrounds highlight the roles that messenger RNAs and small RNAs can play in biology and medicine. While covering the five major RNA-based drugs, namely the use of ribozymes to cleave and/or correct mRNA transcript, the use of siRNA for targeted silencing of gene transcripts, the use of aptamers, like short RNA molecules, for neutralizing the protein functions, the use mRNA-transfected DCs to activate immune system against tumor cells, as well as the use of RNA to reprogram T and/or DC cell function, this extensive volume brings together the fields of coding (mRNA) and non-coding RNA such as ribozymes, RNAse P, siRNAs, and miRNAs into one convenient source. Written in the highly successful .Methods in Molecular Biology.? series format, the cutting-edge protocol chapters contain introductions to their re | | 出版日期 | Book 2010 | | 關(guān)鍵詞 | DNA; Microarray; PCR; Transplantat; Tumor; cloning; gene expression; genes; hybridization; miRNAs; molecular b | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-657-3 | | isbn_softcover | 978-1-4939-6151-1 | | isbn_ebook | 978-1-60761-657-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2010 |
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