Titlebook: RNA Processing; Disease and Genome-w Gene W. Yeo Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spri

可能性

RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLD,y interactions between proteins with prion-like/low-complexity domains (e.g. FUS and TDP-43). We then explore how dysregulation of RNA granule formation is linked to neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), and discuss possible strategies for therapeutic intervention.

Demonstrate

斜谷

Regulation of Tissue-Specific Alternative Splicing: , as a Model System,ur current understanding of tissue and cell-specific regulation in the animal, and emerging techniques that will allow for future mechanistic studies as well as systems level investigations of spatio-temporal splicing under laboratory conditions and in response to environmental stimuli.

留戀

Experimental and Computational Considerations in the Study of RNA-Binding Protein-RNA Interactions,nalysis tools to enable large-scale interpretation in the genomics era. In this chapter we review experimental techniques and challenges in profiling various aspects of RNA processing, as well as recent efforts to develop analyses integrating multiple data sources and techniques to infer RNA regulatory networks.

緯度

高貴領(lǐng)導(dǎo)

debris

Post-Translational Modifications and RNA-Binding Proteins,nctions that a given RNA-binding protein can assume. We will survey the experimental methods that are used to identify the presence of several protein modifications and methods that attempt to discern the consequence of these modifications.

maintenance

Book 2016d neurodegeneration. ?RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying

Mortal

出生