Titlebook: RNA Metabolism in Neurodegenerative Diseases; Rita Sattler,Christopher J. Donnelly Book 2018 Springer International Publishing AG, part of

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Senataxin, A Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From pathology uncovered in familial ALS. Like other RNA processing proteins linked to ALS, the basis for SETX gain-of-function motor neuron toxicity remains ill-defined. Studies of yeast Sen1p and mammalian SETX protein have revealed a range of important RNA regulatory functions, including resolution o

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Mark T. W. Ebbert,Rebecca J. Lank,Veronique V. Belzileters for models which can be extended to larger clusters have also been the focus of SCF/CI and DFT studies. This bootstrap approach is pragmatic, but unsettling. There is always the worry that in mapping the results onto a simpler model, one throws out the baby with the bathwater. In the current c