Titlebook: RNA Infrastructure and Networks; Lesley J. Collins Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive license to S

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Safe Keeping the Message: mRNP Complexes Tweaking after Transcription,messages (transcripts) from the nucleus to the appropriate subcellular compartments and beyond. Presence of mRNPs arbitrates the posttranscriptional control of gene expression by editing the precursor RNA to maturity, postulate its subcellular localization and/or storage and dictate its fate once in

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Unexpected Functions of tRNA and tRNA Processing Enzymes,ation and protein turnover. Induced by stress or as a programmed part of development, nonrandom tRNA fragments can guide mRNA cleavage, inhibit translation and promote morphological changes. Similarly, tRNA processing enzymes, such as RNaseP and tRNA aminoacyl-synthetases participate in tasks affect

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Programmed DNA Elimination in ,: A Small RNA-Mediated Genome Surveillance Mechanism,ry RNAs for degradation. During the past several years, it has been demonstrated that RNAi-related processes are also involved in transcriptional gene silencing by directing formation of heterochromatin. The dynamic DNA rearrangement during sexual reproduction of the ciliated protozoan . provides an

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Long Noncoding RNA and Epigenomics,anscribed to encode a complex network of small and long noncoding RNAs. Long noncoding RNAs are of particular interest, as they were once thought to be restricted to housekeeping functions and are now linked to a wide variety of biological functions related to physiology, embryology and development.

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Erythropoietin

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RNA Networks in Prokaryotes II: tRNA Processing and Small RNAs,s chapter will continue the discussion of prokaryotic molecular systems, showing how these systems can interact with each other to gain a higher level of control within the cell. Our examples include RNase P, the tRNA cleaving molecule that, as well as performing other functions, also cleaves certai

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Localization of the Bacterial RNA Infrastructure,cessing and stability, translation, and protein secretion are conserved. The major difference is that all of these functions take place in a single cellular compartment. In spite of the absence of membrane-bound organelles, or in some cases because of it, key components of the RNA network are locali

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Small RNA Discovery and Characterisation in Eukaryotes Using High-Throughput Approaches,ished based on nucleotide sequence complementarity between the sRNAs and their targets. The development of new high-throughput sequencing technologies has accelerated the discovery of sRNAs in a variety of plants and animals. The use of these and other high-throughput technologies, such as microarra

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