Titlebook: Rho Family GTPases; Ed. Manser (Principle Investigator) Book 2005 Springer Science+Business Media B.V. 2005 Regulation.cell biology.conser

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書目名稱Rho Family GTPases影響因子(影響力)




書目名稱Rho Family GTPases影響因子(影響力)學(xué)科排名




書目名稱Rho Family GTPases網(wǎng)絡(luò)公開度




書目名稱Rho Family GTPases網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Rho Family GTPases被引頻次




書目名稱Rho Family GTPases被引頻次學(xué)科排名




書目名稱Rho Family GTPases年度引用




書目名稱Rho Family GTPases年度引用學(xué)科排名




書目名稱Rho Family GTPases讀者反饋




書目名稱Rho Family GTPases讀者反饋學(xué)科排名

moratorium

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Proteins and Cell Regulationhttp://image.papertrans.cn/r/image/820133.jpg

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https://doi.org/10.1007/1-4020-3462-8Regulation; cell biology; conservation; genecell; proteins; signal transduction; transcription; Proteomics

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The Rho GTPases,ytoskeleton, regulate cell polarity, microtubule dynamics, membrane transport pathways and modulate a variety of transcriptional events. Rho GTPases are biochemically and structually simple proteins: they cycle between two conformational states, with the GTP-bound form regarded as active, while the

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Structural Analysis of Rho Protein Complexes,actions. They include the classical switch regions in the nucleotide-binding site, and a unique switch region located on the opposite side of the protein. These switch regions communicate with each other and couple activation of Arfs by GTP to their recruitment to membranes. Variations in this cycle

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Activation of GTPases by Dock180 Family of Proteins,l GTPases. While conventional GEFs use a conserved DH-PH cassette for catalyzing GTP/GDP nucleotide exchange on Rho family GTPases, the Dock180 family members mediate nucleotide exchange via a novel evolutionarily conserved Docker/DHR2/CZH2 domain. The activation of distinct Rho-family GTPases by pa

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