Titlebook: R-Loops; Methods and Protocol Andrés Aguilera,Alexey Ruzov Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive licen

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,Detection and Quantification of RNA Modifications on RNA–DNA Hybrids Using SID-UPLC-MS/MS,urce of genomic instability and are involved in regulation of several important biological processes in eukaryotic cells. A growing body of experimental evidence suggests that RNA moieties of RNA–DNA hybrids may convey RNA modifications influencing various aspects of R-loop biology. Here we present

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