Titlebook: Quantitative Structure-Activity Relationships; Proceedings of the C Miloň Tichy Conference proceedings 1976 Springer Basel AG 1976 Biologie

PON

CLAMP

M. K?cha?,V. Rejholec,V. Rábek,B. Br?nová,O. Němecěk

遺忘

碎石頭

割公牛膨脹

On the Parabolic Relationship Between Biological Activity and Hydrophobicity of Drugs: Transport or ce may be due to transport processes, but it may also be due to hydrophobic interactions with a recepting protein [3, 4]. The purpose of the present paper is to discuss some criteria which may be helpful to discriminate between these two possibilities and, furthermore, to show that hydrophobic inter

lacrimal-gland

硬化

Emmenagogue

Substructural Analysis in Drug Designted with the names of Hansch [1] and Free and Wilson [2]. A severe limitation shared by these methods is their restriction to structurally closely related series of compounds. Thus they are inappropriate for: a) correlation of data where compounds fall into many different structural series or into n

ADOPT

Stucture-Activity Relationships in a Series of Cinnamic Acids in the Stabilizing Action on Erythrocyn view of the marked antiinflammatory activity found in arylaliphatic acids, we synthesized a series of cinnamic acids substituted on the aromatic ring and branched in the α-position in relation to the carboxyl group (Fig. 1). These compounds were concurrently tested for both antiinflammatory activi

ungainly