| 書目名稱 | Protocols for Oligonucleotides and Analogs | | 副標(biāo)題 | Synthesis and Proper | | 編輯 | Sudhir Agrawal | | 視頻video | http://file.papertrans.cn/762/761970/761970.mp4 | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | When first conceived, not only was the aim of Protocols for Oligo- nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in the area of DNA-based diagnostic and "antisense oligonucleotid- based therapeutic approaches. However, oligonucleotides are now also being used as therapeutic agents and are thus frequently found in clinical trials in humans. Synthesis of unmodified oligonucleotides using automated synthe- sizers has become a common practice in numerous laboratories. How- ever, improvements on the existing techniques and the introduction of ever newer methods for oligonucleotide synthesis is constantly driving | | 出版日期 | Book 1993 | | 版次 | 1 | | doi | https://doi.org/10.1385/0896032817 | | isbn_softcover | 978-0-89603-247-7 | | isbn_ebook | 978-1-59259-507-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 1993 |
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