| 書目名稱 | Proteomics for Drug Discovery | | 編輯 | Josip Blonder | | 視頻video | http://file.papertrans.cn/762/761876/761876.mp4 | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 叢書名稱 | Methods in Molecular Biology | | 圖書封面 |  | | 描述 | .This detailed volume explores a wide range of experimental and bioinformatic proteomics methods applicable to the drug discovery process. Focused on drug target discovery, validation, characterization, and quantitation, the book delves into bottom-up data-dependent (DDA) shotgun and data-independent acquisition (DIA) proteomics, cell surface proteomics, proteogenomics, chemoproteomics, methodologies focused on posttranslational modifications, single cell proteomics, 3D cell culture proteomics, organoids, and laser capture microdissection (LCM) assisted tissue proteogenomics. Advanced quantitative techniques, which include label-free, mass tagging, and targeted immuno-MRM proteomics, along with top-down proteomics for validation and characterization of selected protein targets, are also described. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding foreseeable pitfalls...?..Authoritative and practical, .Proteomics for Drug Discovery. serves as an ideal guide | | 出版日期 | Book 2024 | | 關鍵詞 | Pharmaceutical targets; Drug target identification; Drug discovery and development; Proteomic-based app | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-0716-3922-1 | | isbn_softcover | 978-1-0716-3924-5 | | isbn_ebook | 978-1-0716-3922-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Leidos Biomedical Research Inc. 2024 |
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