| 書目名稱 | Proteinkinase Inhibitors | | 編輯 | Stefan Laufer | | 視頻video | http://file.papertrans.cn/762/761828/761828.mp4 | | 概述 | Reviews proteinkinase inhibitors.Exploits kinase inhibitors for cancer treatment.Offers an authoritative perspective from industry and academia | | 叢書名稱 | Topics in Medicinal Chemistry | | 圖書封面 |  | | 描述 | .This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book..Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.. | | 出版日期 | Book 2021 | | 關鍵詞 | ProteinKinase; Receptor Tyrosine Kinases; EGFR; VEGFR; PDGFR; Protein Kinase Inhibitors; Topology of Prote | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-68180-7 | | isbn_softcover | 978-3-030-68182-1 | | isbn_ebook | 978-3-030-68180-7Series ISSN 1862-2461 Series E-ISSN 1862-247X | | issn_series | 1862-2461 | | copyright | Springer Nature Switzerland AG 2021 |
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