| 書目名稱 | Proteases in Human Diseases | | 編輯 | Sajal Chakraborti,Tapati Chakraborti,Naranjan S. D | | 視頻video | http://file.papertrans.cn/762/761556/761556.mp4 | | 概述 | Provides a comprehensive investigation into the regulation of proteases and their pathological consequences in health and disease.Explores the specific inhibitors and molecular probes for proteases to | | 圖書封面 |  | | 描述 | .This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions..Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life functions of an organism. Under physiological conditions, proteases are regulated by their endogenous inhibitors; however, when the activity of proteases is not regulated appropriately, disease processes can result in. So, there is absolute need for a stringent control of proteolytic activitiesin cells and tissues..Dysregulation of proteases may cause derangement of cellular signalling network resulting in different pathophysiological conditions such as vascular remodelling, atherosclerotic plaque p | | 出版日期 | Book 2017 | | 關(guān)鍵詞 | Proteases; Human Diseases; Cancer; Pharceutical; Medicine | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-3162-5 | | isbn_softcover | 978-981-10-9806-2 | | isbn_ebook | 978-981-10-3162-5 | | copyright | Springer Nature Singapore Pte Ltd. 2017 |
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