| 書目名稱 | Predictive Drug Testing on Human Tumor Cells |
| 編輯 | Victor Hofmann,Michael E. Berens,Georg Martz |
| 視頻video | http://file.papertrans.cn/755/754587/754587.mp4 |
| 叢書名稱 | Recent Results in Cancer Research |
| 圖書封面 |  |
| 描述 | Predictive drug testing on human tumor cells in order to define the appropriate chemotherapy will remain imperative as long as the anticancer agents available are few in number and show only limited activity. The advantages of an effective test would lie in obviating the need for testing antineoplastic agents on large cohorts of patients for assessment of drug activity (phase II studies) and in allowing determination of optimal use of anticancer agents (phase III trials). Such an in vitro test could help to better define dose and schedule of drugs preclinically. The additive value of individual drugs could be determined on tumor cells in vitro in order to define the best combination chemotherapy in vivo. Test-directed therapy would avoid unnecessary drug-related morbidity in patients with refractory tumors. Chemotherapy treatment would be more than justified even with side effects if palliation or even prolonged survival could be anticipated as a result. The benefits of predictive drug testing on human tumor cells would extend beyond improvement of individual patient treatment if the testing helped to identify new active agents. This spectrum of benefits to the entire field of onco |
| 出版日期 | Book 1984 |
| 關(guān)鍵詞 | Cells; cancer; chemotherapy; drug; morbidity; tumor; tumors |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-82295-7 |
| isbn_softcover | 978-3-642-82297-1 |
| isbn_ebook | 978-3-642-82295-7Series ISSN 0080-0015 Series E-ISSN 2197-6767 |
| issn_series | 0080-0015 |
| copyright | Springer-Verlag Berlin Heidelberg 1984 |
|Archiver|手機版|小黑屋|
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