| 書目名稱 | Platelets and Their Factors | | 編輯 | Franz Bruchhausen,Ulrich Walter | | 視頻video | http://file.papertrans.cn/750/749318/749318.mp4 | | 叢書名稱 | Handbook of Experimental Pharmacology | | 圖書封面 |  | | 描述 | Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and clinical research. Platelets, especially human platelets, have also emerged as one of the major models for the study of inter- and intracellular signal transduction pathways. Many biochemists, cell biologists, pharmacologists, pathologists, hematologists, and cardiologists find platelets useful for studying processes such as adhesion, inside-out and outside-in signalling through the plasma membrane, channels, calcium homeostasis, protein kinases, the network of intracellular signal transduction cas | | 出版日期 | Book 1997 | | 關(guān)鍵詞 | Calcium; Nucleotide; Purine; biochemistry; biomolecule; cardiovascular disease; enzymes; metabolism; pathoph | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-60639-7 | | isbn_softcover | 978-3-642-64488-7 | | isbn_ebook | 978-3-642-60639-7Series ISSN 0171-2004 Series E-ISSN 1865-0325 | | issn_series | 0171-2004 | | copyright | Springer-Verlag Berlin Heidelberg 1997 |
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