Titlebook: Paraoxonases in Inflammation, Infection, and Toxicology; Srinivasa T. Reddy Conference proceedings 2010 The Editor(s) (if applicable) and

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,Paraoxonase 1 Interactions with HDL, Antioxidants and Macrophages Regulate Atherogenesis – A Protective Role for HDL Phospholipids,jor players regulate atherosclerosis development; paraoxonase 1 (PON1), antioxidants, and HDL. PON1 is an HDL-associated lactonase which posses antioxidant and anti-atherogenic properties. PON1 protects against macrophage-mediated LDL oxidation, and increases HDL binding to macrophages which, in tur

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The Effect of HDL Mimetic Peptide 4F on PON1,a membrane, in low-density lipoprotein (LDL), against bacterial endotoxin and against toxic agents such as pesticide residues including organophosphates. In circulation, the high-density lipoprotein (HDL)-associated PON1 has the ability to prevent the formation of proinflammatory oxidized phospholip

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Paraoxonase 1, Quorum Sensing, and , Infection: A Novel Model,ng molecules called acyl-homoserine lactones (AHLs), populations of . can coordinate phenotypic changes, including biofilm formation and virulence factor secretion. This concentration-dependent process is called quorum sensing (QS). Interference with QS has been identified as a potential source of n

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