Titlebook: Ovulation Induction and Controlled Ovarian Stimulation; A Practical Guide Roy Homburg Book 2014Latest edition Springer International Publis

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Anti-oestrogens,se inhibitor, is given orally in a dose of 2.5–5 mg/day and is almost free of side effects. In an RCT, 750 women with anovulatory PCOS were randomized to receive either clomifene or letrozole. A 44 % increase in pregnancy rate was achieved by letrozole over clomifene (27.5 % vs 19.5 %). Twinning rat

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Low-Dose Gonadotrophin Therapy for Ovulation Induction,of OHSS and multiple pregnancies. It produces a remarkably consistent rate of uniovulatory cycles of around 70 %, a pregnancy rate of 40 % and an extraordinarily low prevalence of OHSS which was almost completely eliminated and a multiple pregnancy rate of 5.7 %. The majority of patients (90 %) on a

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Controlled Ovarian Stimulation for IVF/ICSI,ver the agonist as regards patient comfort. Pre-treatment predictions of high, low and normal responders (using age, AMH and/or AFC) determines the protocol to be used and the starting dose of stimulation.

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Management of Poor Responders,atment modalities that have been proposed for the poor responder, bearing witness that none of them have been successful and that you cannot stimulate follicles that aren’t there. Only testosterone patches and letrozole have offered some glimmer of hope for treating the poor responder but evidence i

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Mild Stimulation Protocols,. A so-called modified natural cycle employing mild stimulation and a GnRH antagonist has also produced disappointing results. The integration of clomifene and of letrozole into protocols has decreased gonadotrophin consumption but little else. The principles involved in the search for an efficient